WELCOME TO GREENGATE GENOMICS

Bioinformatic
solutions

for complex microbiomes

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ABOUT
GREENGATE GENOMICS

GreenGate Genomics is a cutting-edge bioinformatic service startup specializing in microbial and environmental genomics. Founded in 2023 by five researchers at the GFZ German Research Center for Geosciences, we are at the forefront of deciphering the world of microbial genetic data. With a team of skilled bioinformaticians and molecular microbiologists, we utilize advanced, state-of-the-art techniques and workflows to provide comprehensive analysis and interpretation of microbial genomes. Our tailored services cater to the unique needs of academic researchers, biotech companies, and healthcare professionals, equipping them with invaluable insights into the complexities of microbial systems

GREENGATE GENOMICS
SERVICES

GreenGate Genomics is offering services in genomic and bioinformatic analyses with special expertise in microbiology and molecular biology. 

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GreenGate’s services support scientists, institutes and companies through customized data analysis, the creation of analysis workflows and pipelines, and/or the development and implementation of bioinformatic training and workshops.

AMPLICON DATA BASED SERVICES

DNA based

  • Barcode/Primer Design 
  • Quality Control Workflows
  • ASV/OTU Identification
  • Taxonomic Assessments
  • Marker Gene Analysis
Details

OXFORD NANOPORE DATA SERVICES

DNA based

  • Sequencing
  • High Accuracy Basecalling
  • Error Correction
  • Genome Assembly
  • Metagenomic Analysis
Details

ILLUMINA DATA SERVICEs

DNA based

  • Raw Data Processing (paired-end / single-end)
  • High Quality Co-assemblies
  • Metagenomic Analysis
  • Annotation
Details

METATRANSCRIPTOMIC ANALYSIS SERVICES

RNA based

  • Raw Data (paired-end or single-end) quality check
  • Assembly and Gene Calling
  • Functional and Taxonomic Annotation of Genes
  • Differential Expression
Details

CONSULTATION AND EDUCATION SERVICES

HELP aND PROJECT SUPPORT

  • Consultation on Experiment Design
  • Project-specific Sequencing  Recommendations
  • Data Analysis Strategy Selection
  • Training and Workshops
Details

Data Visualization and Biostatistics

DATA DEEP DIVE

  • Custom Figures and Plots 
  • Rarefaction and Rank Abundance Curves
  • Alpha/Beta Diversity  assessment
  • Indicator Species Analysis
  • Generalist and Specialist Taxa selection
Details

GREENGATE GENOMICS
TEAM

Alexander Bartholomäus
Chief Execution Officer (CEO)
Sizhong Yang
Chief Technical Officer (CTO)
Daniel Lipus
Chief Customer Officer (CCO)
Susanne Liebner
Scientific Advisor
Dirk Wagner
Scientific Advisor

Learn more about the Team here!

GREENGATE GENOMICS
CASE STUDIES

We at GreenGate Genomics have extensive expertise working in the field of environmental microbial genomics. Some of the projects we have participated in are listed  below. Our work has also been published in numerous peer reviewed research articles in renowned scientific journal. Please have a look at our publications page.

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Oil and Gas Ecology

Evaluation of microbial abundance and composition patterns highlighted elevated potential for biocorrosion and well fouling. Statistical assessment suggested a link between biocide usage and microbial distribution. Reconstruction and characterization of draft genomes provided insights into microbial processes in oil and gas environments
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Methane-Cycling Microbiome in Permafrost

Taxonomic and functional profiling revealed high diversity of methane cycling microbiome residing in permafrost soil, with heterogeneous distribution patterns in active layer and permafrost. Diversity loss after excessive warming will lead to larger variability of production rate of greenhouse gas CH4 and CO2 from permafrost soils
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Deep Biosphere

Specifically adapted laboratory and bioinformatic workflows allowed the reconstruction of microbial distribution patterns down to a depth of 230 m across this, difficult to work with, low biomass environment. Metagenomic genome recovery allowed the detection and characterization of CO2 utilizing methangenic and chemolithotrophic mcirroganismans. Statistical evaluation provided insights into microbial co-occurrence patterns and bio-geo interactions.
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Biocide Resistance

Differential expression analysis resulted in the identification of significantly upand downregulated genes in response to sodium hypochlorite. Following annotation of these genes, results were used to reconstruct cellular pathways which may be used by Pseudomonas biofilm cells to develop resistance to oxidative biocides.
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Atacama Desert

Evaluating the extracellular and intracellular DNA fractions in soil and rock samples from different Atacama desert locations, it was possible to identify highly adapted microbial species, investigate their response to extreme arditty and UV exposure, and gather important insights on microbial turnover in Mars like environments.
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Nanopore Genome Sequencing

Oxford Nanopore Technologies (ONT) offers long read sequencing by nanopore sequencing. Long reads are well suited for genome reconstruction, still the workflow requires careful execution of different computational steps from basecalling to binning of final genome. Some steps of this workflow have a high influence on the size and quality of the final genome.

© 2023 greengategenomics.com

© 2023 greengategenomics.com